Herpes Simplex Encephalitis

An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

Also Known As:

Herpes Encephalitis; Encephalitis, Herpes; Encephalitis, Herpes Simplex; Acute Necrotizing Encephalitis, Herpetic; Herpes Simplex Meningoencephalitis; Herpetic Encephalitis; Herpetic Meningoencephalitis; Encephalitides, Herpes Simplex; Encephalitides, Herpetic; Encephalitis, Herpetic; Herpes Simplex Encephalitides; Herpes Simplex Meningoencephalitides; Herpetic Encephalitides; Herpetic Meningoencephalitides; Meningoencephalitides, Herpes Simplex; Meningoencephalitides, Herpetic; Meningoencephalitis, Herpes Simplex; Meningoencephalitis, Herpetic; Herpetic Acute Necrotizing Encephalitis; Meningoencephalitis, Herpes Simplex Virus

Infections: 539155
- Virus Diseases: 42919
  - DNA Virus Infections: 145
    - Herpesviridae Infections: 836
      - Herpes Simplex Encephalitis: 736
  - Central Nervous System Viral Diseases: 47
    - Viral Encephalitis: 480
      - Herpes Simplex Encephalitis: 736
- Central Nervous System Infections: 1428
  - Infectious Encephalitis: 58
    - Viral Encephalitis: 480
      - Herpes Simplex Encephalitis: 736
  - Central Nervous System Viral Diseases: 47
    - Viral Encephalitis: 480
      - Herpes Simplex Encephalitis: 736
Nervous System Diseases: 14737
- Neuroinflammatory Diseases: 19509
  - Encephalitis: 8670
    - Infectious Encephalitis: 58
      - Viral Encephalitis: 480
        Herpes Simplex Encephalitis: 736
- Central Nervous System Diseases: 4371
  - Brain Diseases: 16141
    - Encephalitis: 8670
      - Infectious Encephalitis: 58
        Viral Encephalitis: 480
        Herpes Simplex Encephalitis: 736
  - Central Nervous System Infections: 1428
    - Infectious Encephalitis: 58
      - Viral Encephalitis: 480
        Herpes Simplex Encephalitis: 736
    - Central Nervous System Viral Diseases: 47
      - Viral Encephalitis: 480
        Herpes Simplex Encephalitis: 736

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Drug/Important Bio-Agent (IBA)